Pulmonary hypertension on CT

CT

First and second year — the floor first, then every step

Measure the main pulmonary artery against the ascending aorta, look at the right heart, then search for the cause — chronic thromboembolism, lung disease, a shunt or left heart disease — because the cause is the report.

Orient first

  • Pulmonary hypertension is diagnosed by right heart catheterisation; CT suggests it and, more usefully, suggests its group.
  • A main pulmonary artery diameter above about 29–30 mm, or wider than the adjacent ascending aorta, raises the possibility — verify the threshold used locally.
  • Chronic thromboembolic disease is the treatable cause not to miss: eccentric mural thrombus, webs and bands, mosaic perfusion.

Acquire the study

  • CT pulmonary angiography with thin slices; lung windows for parenchymal disease; ECG gating is optional.

The manoeuvre

  • Axial slice at the bifurcation: main pulmonary artery diameter in mm and its ratio to the ascending aorta.
  • Right heart: RV/LV diameter ratio on axial images, septal flattening, contrast reflux into the IVC and hepatic veins.
  • Arterial phase: eccentric thrombus, webs, abrupt narrowing and pouching (chronic thromboembolism); bronchial artery hypertrophy.
  • Lung window: mosaic attenuation, emphysema, fibrosis, centrilobular ground-glass nodules (veno-occlusive disease).
  • Shunts and the left heart: atrial or ventricular septal defect, anomalous venous return, left atrial enlargement.

What confirms it

  • An enlarged pulmonary trunk with right heart strain and a named likely group.

What licenses you to exclude it

  • A normal-calibre pulmonary artery does not exclude pulmonary hypertension; echocardiography and catheterisation decide.

The classic misread

  • Missing chronic thromboembolic disease because the eye is trained on acute emboli — look for webs and eccentric thrombus.

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. Approach to Pulmonary Hypertension: From CT to Clinical Diagnosis ↗Aluja Jaramillo F, Gutierrez FR, Díaz Telli FG, et al. · RadioGraphics 2018RSNA · PubMed
  2. CT findings in diseases associated with pulmonary hypertension: a current review ↗Grosse C, Grosse A · RadioGraphics 2010RSNA · PubMed
  3. The diagnostic performance of CT pulmonary angiography in the detection of chronic thromboembolic pulmonary hypertension-systematic review and meta-analysis ↗Lambert L, Michalek P, Burgetova A · European Radiology 2022ESR · PubMed
  4. Computed tomography appearances of the lung parenchyma in pulmonary hypertension ↗Foley RW, Kaneria N, Ross RVM, et al. · British Journal of Radiology 2021BIR · PubMed

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