Grading internal carotid artery stenosis

USG · CT

First and second year — the floor first, then every step

On Doppler, grade by the peak systolic velocity and the ICA/CCA ratio together with the grey-scale plaque; on CTA, measure by NASCET — the narrowest lumen against the normal distal ICA.

Orient first

  • NASCET compares the narrowest residual lumen with the normal ICA distal to the bulb; ECST compares it with the estimated original bulb diameter — they give different percentages for the same artery.
  • Doppler velocity criteria (e.g. the SRU consensus) grade in bands; the numbers depend on the criteria set your lab uses — verify.
  • Near-occlusion collapses the distal ICA and velocities can fall — a trap that makes a critical stenosis look milder.

Acquire the study

  • Linear probe; grey-scale, colour and spectral Doppler of the CCA, bulb, ICA and ECA; angle ≤ 60° parallel to flow.

The manoeuvre

  • Grey-scale in longitudinal and transverse planes: plaque location, surface (irregular, ulcerated) and echogenicity.
  • Spectral Doppler with angle correction ≤ 60°: peak systolic velocity at the tightest point and just beyond it; end-diastolic velocity.
  • ICA/CCA peak systolic velocity ratio — compare with the contralateral side.
  • Vertebral arteries on colour Doppler: direction of flow (subclavian steal).

What confirms it

  • A stenosis category consistent across velocity, ratio and plaque, or a NASCET percentage on CTA.

What licenses you to exclude it

  • A normal duplex with good windows excludes significant ICA stenosis at the bifurcation; intracranial disease needs other imaging.

The classic misread

  • Grading a contralateral compensatory high velocity as stenosis — compare both sides.

Reference values

Each value carries the caveat that keeps it from being misused. Normal limits and diagnostic criteria are kept apart on purpose: a disease cut-off read as a normal range is the more dangerous mistake.

Normal limits

  • Carotid bulb · Expected flare of the bulb

    the bulb is normally wider than the CCA — that flare is anatomy, not an aneurysm; plaque burden is reported with NASCET-style percent (vascular shelf)

    Do not call a normal bulb an aneurysm. Stenosis measurement belongs on the vascular shelf (NASCET vs ECST), not as a millimetre of bulb width.

    USG · CT

Diagnostic criteria

  • Internal carotid artery (percent stenosis) · NASCET versus ECST percent — how to report it

    NASCET = (1 − residual lumen / distal ICA) × 100; ECST = (1 − residual lumen / estimated bulb) × 100. The same plaque is a HIGHER percent on ECST — state which method

    State which method. On CTA/MRA measure residual lumen against the distal ICA (NASCET) or against a reconstructed bulb (ECST). Doppler criteria (next entry) are calibrated mainly to NASCET.

    ⚠️ A "70% stenosis" without the method is unreadable and can move a patient across an operating threshold. Doppler SRU bands below are NASCET-referenced.

    USG · CT · MRI

  • Internal carotid artery · ICA PSV, EDV and ICA/CCA ratio (SRU consensus)

    SRU 2003 consensus (NASCET-referenced): PSV <125 cm/s is <50%; 125–230 cm/s is 50–69%; >230 cm/s is ≥70%, with EDV and ICA/CCA ratio as concordant criteria

    Angle-corrected Doppler ≤60° in the tightest ICA segment; CCA PSV in a disease-free mid-CCA. Concordance of PSV, EDV (>100 cm/s for ≥70%) and ratio (>4 for ≥70%) is the test, not one number.

    Near-occlusion can DROP the PSV — a trickle with a collapsed distal ICA is not "mild". Contralateral occlusion raises ipsilateral velocities. Confirm the laboratory still uses SRU 2003 or a named successor. Versioned criterion — verify against the current edition before clinical use.

    USG

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. Carotid artery stenosis: gray-scale and Doppler US diagnosis--Society of Radiologists in Ultrasound Consensus Conference ↗Grant EG, Benson CB, Moneta GL, et al. · Radiology 2003RSNA · PubMed
  2. Carotid artery stenosis: accuracy of noninvasive tests--individual patient data meta-analysis ↗Chappell FM, Wardlaw JM, Young GR, et al. · Radiology 2009RSNA · PubMed
  3. Carotid Near-Occlusion: A Comprehensive Review, Part 1--Definition, Terminology, and Diagnosis ↗Johansson E, Fox AJ · AJNR 2016ASNR · PubMed
  4. Accuracy of the Society of Radiologists in Ultrasound (SRU) Carotid Doppler Velocity Criteria for Grading North American Symptomatic Carotid Endarterectomy Trial (NASCET) Stenosis: A Meta-Analysis ↗Polak JF, Alexandrov AV · Journal of Ultrasound in Medicine 2023AIUM · PubMed
  5. Advances in Multimodality Carotid Plaque Imaging: AJR Expert Panel Narrative Review ↗Bos D, van Dam-Nolen DHK, Gupta A, et al. · AJR 2021ARRS · PubMed

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