Assessing myocardial viability with late gadolinium enhancement

MRI

First and second year — the floor first, then every step

The transmural extent of LGE in each segment predicts recovery after revascularisation: < 25% likely to recover, > 50% unlikely — report per segment on the 17-segment model with LV volumes and EF.

Orient first

  • Infarct LGE is subendocardial, extending towards the epicardium in a coronary territory.
  • Dysfunctional segments with little LGE are viable (hibernating or stunned).
  • Low-dose dobutamine contractile reserve adds information in intermediate segments (verify local practice).

Acquire the study

  • CMR: cine short-axis stack; LGE (PSIR) 10–15 min after gadolinium in short axis and long axes; microvascular obstruction on early gadolinium imaging.

The manoeuvre

  • Cine: wall motion per segment (normal, hypo-, a-, dyskinetic) and end-diastolic wall thickness in mm.
  • LGE per segment: transmural extent 0, 1–25, 26–50, 51–75, 76–100%.
  • Microvascular obstruction (dark core) on early and late gadolinium.
  • LV thrombus; LV volumes and EF indexed.
  • Summarise the number of viable dysfunctional segments per territory.

What confirms it

  • A segmental map of transmurality that matches the coronary anatomy.

What licenses you to exclude it

  • No LGE in dysfunctional segments means viable myocardium (or a non-ischaemic cause).

The classic misread

  • Wrong inversion time making the whole myocardium grey — scar underestimated.

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