Grading hepatic steatosis — and saying which method measured it

USG · CT · MRI

First and second year — the floor first, then every step

Fat is graded qualitatively on ultrasound, estimated from unenhanced CT attenuation, and measured on MRI proton-density fat fraction; the report names the method and the number, and looks for focal fat and sparing that mimic lesions.

Orient first

  • MRI-PDFF is the quantitative reference (fat fraction in %); ultrasound attenuation parameters (CAP, dB/m or dB/cm/MHz) are vendor-dependent.
  • Each method has its own threshold — MRI fat fraction, CT attenuation against the spleen, ultrasound attenuation — so the report names the method with the value.
  • Focal fat and focal sparing occur at typical sites: around the gallbladder fossa, the falciform ligament, segment IV anterior to the porta.

Acquire the study

  • Curvilinear probe; compare liver and right kidney at the same depth; attenuation measurement per vendor protocol.

The manoeuvre

  • Liver echogenicity compared with the renal cortex at the same depth.
  • Beam attenuation: poor visualisation of the diaphragm and deep portal vein walls = higher grade.
  • Report the attenuation value with its unit and vendor.
  • Focal sparing: geographic hypoechoic areas at typical sites, no mass effect.

What confirms it

  • A quantitative value (PDFF, attenuation or HU) above the method-specific threshold.

What licenses you to exclude it

  • A normal PDFF excludes steatosis; a qualitative normal ultrasound does not exclude mild steatosis.

The classic misread

  • Grading on a machine with gain set too high.

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